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Sexual health and LGBT population
Living with HIV
Post-exposure prophylaxis (PEP)
In 1996, the currently recommended triple therapy approach (the combination of three different antiretrovirals) was first widely recognized as the best way to manage HIV infection
Prior to the onset of triple therapy, the use of single ARV or double combinations of ARVs permitted the virus to quite rapidly develop resistance to the medications used thus permitting the virus to "break through" therapy and continue to reproduce despite medications — please refer to the section What is medication resistance?
Current recommended therapies to control HIV are all permutations of combinations of at least three currently available antiretroviral agents. The logic behind this approach is that it greatly decreases the risk that the virus develops resistance to the medications employed. If resistance is unable to develop, therapy should, in theory, work forever.