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Commonly referred to as fever blisters, cold sores are highly contagious ulcers or blisters that form on the outer edge of the mouth, and generally last for seven to ten days. Those who suffer from cold sores typically feel a tingling sensation just beneath the surface of the skin before the blisters actually form. People with cold sores are advised to avoid kissing, or direct contact with the sores, and to wash their hands immediately after touching the sore.
It is estimated that 20 to 40 per cent of the adult population suffer from cold sores. Typically, cold sore sufferers will experience three to four outbreaks every year. Exposure to certain triggers including sunlight, stress, fatigue, and hormonal changes can cause a cold sore outbreak.
The recommended dosage of Valtrex© for cold sores is two grams twice daily for one day only (24-hour period). The second dose should be taken approximately 12 hours after the first dose, but not less than six hours after the first dose. Therapy should be initiated at the earliest symptom of a cold sore (e.g., tingling, itching or burning). There are no data on the efficacy of treatment initiated after the development of clinical signs of a cold sore (e.g., blister, bump or open sore). Possible side effects with Valtrex© for cold sores include headache and dizziness.